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Thalassaemias Condition Genetic defect Clinical options Homozygous fi fi chain suppression Severe anaemia: Hb <7 g/dl thalassaemia or deletion Dependent on transfusion (fi thalassaemia main) Heterozygous fi fi chain deletion Asymptomatic: mild anaemia: thalassaemia Hb >10 g/dl (fi thalassaemia minor trait) Thalassaemia fi chain suppression Heterogeneous: ranges from intermedia or deletion asymptomatic to resembling fi thalassaemia main: Hb 7пїЅ10 g/dl Homozygous fi All 4 fi globin chains Fetus does not survive thalassaemia deleted (hydrops fetalis) fi thalassaemia minor Loss of two or three Usually gentle or reasonable fi genes fi thalassaemia trait Loss of 1 or two Symptomless: gentle microcytic, fi genes hypochromic anaemia 104 the differentiation at presentation between thalassaemia intermedia and main is essential in figuring out applicable therapy. Sassi S, Cosmi B, Palareti G, Legnani C, Grossi G, Musolesi S, Coccheri Chim Acta. Given this terminological controversy, it is medial side of the frontoparietal space erectile dysfunction korea buy tadalafil mastercard.
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